Installation¶
Prerequisites¶
- Python 3.10 or later
- A C compiler (required by pysam and bx-python)
Install from PyPI¶
Or with uv:
Install from source¶
Verify installation¶
System dependencies¶
Some dependencies require system libraries:
- pysam requires
htslibheaders. On most systems, pip will build from source automatically. If you encounter build errors, installhtslibvia your package manager:- macOS:
brew install htslib - Ubuntu/Debian:
apt install libhts-dev
- macOS:
- pyBigWig requires
libcurlandzlibheaders.
Optional: gene model files¶
Many tools require a reference gene model in BED12 format. See Input Formats for details on obtaining these files.